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Sildenafil improves the influence of NO by inhibiting phosphodiesterase type five (PDE5), that's chargeable for degradation of cGMP while in the corpus cavernosum. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum.Dette kan spesielt være dersom tabletten tas med et stort eller fett måltid kan absorberingen av virkemidde

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Very low Blood pressure level (Hypotension). Sildenafil may possibly induce a delicate and temporary fall in blood pressure level. You may be at a greater danger In case you have sure health ailments or consider hypertension medicines.an erection that will not disappear (priapism). For those who have an erection that lasts much more than four hours

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